Medications used to treat osteoporosis and cancer-related bone disease, including bisphosphonates and other antiresorptive agents, are powerful tools for protecting skeletal health, but they carry an important and often overlooked risk to the jaw. This talk explores a serious condition called Medication-Related Osteonecrosis of the Jaw (MRONJ), where the jawbone loses its ability to heal properly following dental procedures or injury. Whether you are managing osteoporosis or undergoing cancer treatment, understanding this risk can help you and your dental team make safer, more informed decisions together.